Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM50288285 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_3407 | ||
Kd | 0.150000±n/a nM | ||
Citation | Paulis, Td; Trivedi, BL; Zhang, ZJ; Schmidt, DE; Ebert, MH; Hewlett, WA (S)-4-amino-5-chloro-3-iodo-2-methoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide (TRIZAC), a high-affinity ligand for the 5-HT-3 receptor Bioorg Med Chem Lett6:2657-2662 (1996) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_RAT | 5ht3 | Htr3 | Htr3a | Serotonin (5-HT) receptor | Zacopride site-R | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 55428.70 | ||
Organism: | RAT | ||
Description: | 5-HT3 HTR3A RAT::P35563 | ||
Residue: | 483 | ||
Sequence: |
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BDBM50288285 | |||
n/a | |||
Name | BDBM50288285 | ||
Synonyms: | CHEMBL90314 | N-(S)-1-Aza-bicyclo[2.2.2]oct-3-yl-5-chloro-3-iodo-2-methoxy-benzamide | ||
Type | Small organic molecule | ||
Emp. Form. | C15H18ClIN2O2 | ||
Mol. Mass. | 420.673 | ||
SMILES | COc1c(I)cc(Cl)cc1C(=O)N[C@@H]1CN2CCC1CC2 |wU:13.13,(16.29,-14.6,;16.29,-13.05,;14.96,-12.28,;13.61,-13.05,;13.61,-14.67,;12.28,-12.28,;12.28,-10.73,;10.87,-9.92,;13.61,-9.96,;14.96,-10.73,;16.29,-9.96,;16.29,-8.41,;17.64,-10.73,;18.97,-9.96,;20.29,-10.73,;21.62,-9.97,;21.63,-8.44,;20.3,-7.66,;18.95,-8.42,;19.71,-9.75,;21.04,-8.99,)| | ||
Structure |