| Reaction Details |
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 | Report a problem with these data |
| Target | Interstitial collagenase |
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| Ligand | BDBM50288710 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_101755 |
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| Ki | 2200±n/a nM |
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| Citation |  Chapman, KT; Wales, J; Sahoo, SP; Niedzwiecki, LM; Izquierdo-Martin, M; Chang, BC; Harrison, RK; Stein, RL; Hagmann, WK Inhibition of matrix metalloproteinases by P1 substituted N-carboxyalkyl dipeptides Bioorg Med Chem Lett6:329-332 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interstitial collagenase |
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| Name: | Interstitial collagenase |
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| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54010.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03956 |
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| Residue: | 469 |
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| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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| BDBM50288710 |
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| n/a |
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| Name | BDBM50288710 |
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| Synonyms: | (R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-phenyl-propylamino]-5-(3-phenyl-propionylamino)-pentanoic acid | CHEMBL333831 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H46N4O5 |
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| Mol. Mass. | 614.7742 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 |
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| Structure | 
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