| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peptidyl-glycine alpha-amidating monooxygenase |
|---|
| Ligand | BDBM50288770 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_152798 |
|---|
| Ki | 0.190000±n/a nM |
|---|
| Citation |  Casara, P; Ganzhorn, A; Philippo, C; Chanal, MC; Danzin, C Unsaturated thioacetic acids as novel mechanism-based inhibitors of peptidylglycine α-hydroxylating monooxygenase Bioorg Med Chem Lett6:393-396 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peptidyl-glycine alpha-amidating monooxygenase |
|---|
| Name: | Peptidyl-glycine alpha-amidating monooxygenase |
|---|
| Synonyms: | AMD_HUMAN | PAL | PAM | PHM | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase | Peptidylamidoglycolate lyase | Peptidylglycine alpha-hydroxylating monooxygenase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 108328.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_885021 |
|---|
| Residue: | 973 |
|---|
| Sequence: | MAGRVPSLLVLLVFPSSCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVPIDSSDFALD
IRMPGVTPKQSDTYFCMSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWF
CDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKD
CSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHH
LGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATH
IGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEANIPIPVKSDMVMMHE
HHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVVHVHKYNPTEKAESES
DLVAEIANVVQKKDLGRSDAREGAEHERGNAILVRDRIHKFHRLVSTLRPPESRVFSLQQ
PPPGEGTWEPEHTGDFHMEEALDWPGVYLLPGQVSGVALDPKNNLVIFHRGDHVWDGNSF
DSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALH
QVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFS
PSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVR
EIKHSSFGRNVFAISYIPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKHFD
MPHDIVASEDGTVYIGDAHTNTVWKFTLTEKLEHRSVKKAGIEVQEIKEAEAVVETKMEN
KPTSSELQKMQEKQKLIKEPGSGVPVVLITTLLVIPVVVLLAIAIFIRWKKSRAFGDSEH
KLETSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRLSTEGSDQEKEDDGSESEEE
YSAPLPALAPSSS
|
|
|
|---|
| BDBM50288770 |
|---|
| n/a |
|---|
| Name | BDBM50288770 |
|---|
| Synonyms: | CHEMBL335660 | Phenylethynylsulfanyl-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H8O2S |
|---|
| Mol. Mass. | 192.234 |
|---|
| SMILES | OC(=O)CSC#Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
