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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | ||
| Ligand | BDBM50039257 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_202904 | ||
| Ki | 9±n/a nM | ||
| Citation |  Abell, AD; Brandt, M; Levy, MA; Holt, DA A comparison of steroidal and non-steroidal inhibitors of human steroid 5α-reductase: New tricyclic aryl acid inhibitors of the type-1 isozyme Bioorg Med Chem Lett6:481-484 (1996) Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | |||
| Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | ||
| Synonyms: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 5α-Reductase 1 (5α-R1) | S5A1_HUMAN | S5AR | SR type 1 | SRD5A1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 29472.80 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P18405 | ||
| Residue: | 259 | ||
| Sequence: |
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| BDBM50039257 | |||
| n/a | |||
| Name | BDBM50039257 | ||
| Synonyms: | (1S,9aR,11aS)-9a,11a-Dimethyl-1-(3-methyl-butyryl)-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridin-7-one | 9a,11a-Dimethyl-1-(3-methyl-butyryl)-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridin-7-one | CHEMBL420020 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H35NO2 | ||
| Mol. Mass. | 357.5295 | ||
| SMILES | CC(C)CC(=O)[C@H]1CCC2C3CN=C4CC(=O)CC[C@]4(C)C3CC[C@]12C |t:12| | ||
| Structure | 
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