| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50288946 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157722 |
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| Ki | 18±n/a nM |
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| Citation |  Lee, CS; Choy, N; Park, C; Choi, H; Son, YC; Kim, S; Ok, JH; Yoon, H; Kim, SC Design, synthesis, and characterization of dipeptide isostere containing cis-epoxide for the irreversible inactivation of HIV protease Bioorg Med Chem Lett6:589-594 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50288946 |
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| n/a |
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| Name | BDBM50288946 |
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| Synonyms: | 2-{2-[(2R,3S)-3-((S)-1-{3-Carbamoyl-2-[(quinoline-2-carbonyl)-amino]-propionylamino}-2-phenyl-ethyl)-oxiranyl]-acetylamino}-3-methyl-pentanoic acid | CHEMBL157945 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H37N5O7 |
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| Mol. Mass. | 603.6655 |
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| SMILES | CCC(C)C(NC(=O)C[C@H]1O[C@H]1[C@H](Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(O)=O |
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| Structure | 
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