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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50288947
Substrate/Competitorn/a
Meas. Tech.ChEBML_157722
Ki 1±n/a nM
Citation Lee CSChoy NPark CChoi HSon YCKim SOk JHYoon HKim SC Design, synthesis, and characterization of dipeptide isostere containing cis-epoxide for the irreversible inactivation of HIV protease Bioorg Med Chem Lett 6:589-594 (1996)    Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50288947
n/a
NameBDBM50288947
Synonyms:CHEMBL158033 | N*1*-((S)-1-{(2R,3S)-3-[(1-Isopropyl-2-methyl-propylcarbamoyl)-methyl]-oxiranyl}-2-phenyl-ethyl)-2-[(quinoline-2-carbonyl)-amino]-succinamide
TypeSmall organic molecule
Emp. Form.C33H41N5O5
Mol. Mass.587.7091
SMILESCC(C)C(NC(=O)C[C@@H]1O[C@@H]1[C@H](Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(C)C
Structure
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