| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein kinase C eta type |
|---|
| Ligand | BDBM3153 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_161123 |
|---|
| IC50 | 0.600000±n/a nM |
|---|
| Citation |  Hu, H; Hollinshead, SP; Hall, SE; Kalter, K; Ballas, LM Synthesis and protein kinase C inhibitory activities of indane analogs of balanol Bioorg Med Chem Lett6:973-978 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein kinase C eta type |
|---|
| Name: | Protein kinase C eta type |
|---|
| Synonyms: | KPCL_HUMAN | PKC-L | PKCL | PRKCH | PRKCL | Protein Kinase C, eta | Protein kinase C, PKC; classical/novel | nPKC-eta |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 77844.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells |
|---|
| Residue: | 683 |
|---|
| Sequence: | MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
KLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAM
GVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSL
TQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDE
GHLPMINQDEFRNFSYVSPELQP
|
|
|
|---|
| BDBM3153 |
|---|
| n/a |
|---|
| Name | BDBM3153 |
|---|
| Synonyms: | 2-{[2,6-dihydroxy-4-({[(1R,2R)-2-[(4-hydroxybenzene)amido]cyclopentyl]oxy}carbonyl)phenyl]carbonyl}-3-hydroxybenzoic acid | Balanol analog 5 | CHEMBL52529 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H23NO10 |
|---|
| Mol. Mass. | 521.4722 |
|---|
| SMILES | OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
