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TargetMHC class II antigen
LigandBDBM50289278
Substrate/Competitorn/a
Meas. Tech.ChEMBL_192854 (CHEMBL800187)
IC50 6.5±n/a nM
Citation Cunningham, BRRivetna, MTolman, RLFlattery, SJNichols, EASchwartz, CDWicker, LSHermes, JDJones, AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett7:19-24 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
MHC class II antigen
Name:MHC class II antigen
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50289278
n/a
NameBDBM50289278
Synonyms:(S)-2-[(S)-3-Carbamoyl-2-((S)-2-{[(R)-2-ethoxycarbonylamino-3-(4-hydroxy-phenyl)-propionyl]-methyl-amino}-5-guanidino-pentanoylamino)-propionylamino]-3-methyl-butyric acid | CHEMBL75687
TypeSmall organic molecule
Emp. Form.C28H44N8O9
Mol. Mass.636.6972
SMILESCCOC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O
Structure
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