BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMHC class II antigen
LigandBDBM50289251
Substrate/Competitorn/a
Meas. Tech.ChEMBL_192854 (CHEMBL800187)
IC50 230±n/a nM
Citation Cunningham, BRRivetna, MTolman, RLFlattery, SJNichols, EASchwartz, CDWicker, LSHermes, JDJones, AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett7:19-24 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
MHC class II antigen
Name:MHC class II antigen
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50289251
n/a
NameBDBM50289251
Synonyms:((S)-1-{(S)-5-Amino-1-[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester | CHEMBL80176
TypeSmall organic molecule
Emp. Form.C26H42N6O6S
Mol. Mass.566.713
SMILESCCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: