BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetHuman leukocyte antigen DR beta chain
LigandBDBM50289274
Substrate/Competitorn/a
Meas. Tech.ChEMBL_192854
IC50 140±n/a nM
Citation Cunningham BRRivetna MTolman RLFlattery SJNichols EASchwartz CDWicker LSHermes JDJones AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett 7:19-24 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
Human leukocyte antigen DR beta chain
Name:Human leukocyte antigen DR beta chain
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50289274
n/a
NameBDBM50289274
Synonyms:CHEMBL309610 | [(R)-1-{(S)-1-[(S)-1-((S)-1-Carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-(4-nitro-phenyl)-ethyl]-carbamic acid ethyl ester
TypeSmall organic molecule
Emp. Form.C26H40N6O8
Mol. Mass.564.6312
SMILESCCOC(=O)N[C@H](Cc1ccc(cc1)[N+]([O-])=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: