| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50009075 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_52039 |
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| Kd | 30100±n/a nM |
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| Citation |  Zhang, MQ; Zwaagstra, ME; Nederkoorn, PH; Timmerman, H THE ROLE OF ARGININE IN THE BINDING OF LTD4 ANTAGONISTS TO cysLT1 RECEPTORS OF GUINEA PIG LUNG Bioorg Med Chem Lett7:1331-1336 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39007.58 |
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| Organism: | GUINEA PIG |
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| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
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| Residue: | 340 |
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| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
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| BDBM50009075 |
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| n/a |
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| Name | BDBM50009075 |
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| Synonyms: | CHEMBL22033 | ICI 198615 | ICI-198615 | [1-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1H-indazol-5-yl]-carbamic acid cyclopentyl ester | [1-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1H-indazol-6-yl]-carbamic acid cyclopentyl ester | [1-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1H-indazol-6-yl]-carbamic acid cyclopentyl ester (ICI 198,615) | [1-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1H-indazol-6-yl]-carbamic acid cyclopentyl ester(ICI 198, 615) | [1-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1H-indazol-6-yl]-carbamic acid cyclopentyl ester(ICI 198615) |
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| Type | Small organic molecule |
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| Emp. Form. | C28H28N4O6S |
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| Mol. Mass. | 548.61 |
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| SMILES | COc1cc(ccc1Cn1ncc2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1 |
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| Structure | 
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