| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50289441 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_79984 |
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| Ki | 0.100000±n/a nM |
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| Citation |  Smallheer, JM; McHugh, RJ; Chang, CH; Kaltenbach, RF; Worley, TV; Klabe, RM; Bacheler, LT; Rayner, MM; Erickson-Viitanen, S; Seitz, SP Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323 Bioorg Med Chem Lett7:1365-1370 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50289441 |
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| n/a |
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| Name | BDBM50289441 |
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| Synonyms: | (4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1-(4-hydroxymethyl-benzyl)-3-(5-hydroxy-pentyl)-[1,3]diazepan-2-one | CHEMBL285354 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H40N2O5 |
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| Mol. Mass. | 532.6704 |
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| SMILES | OCCCCCN1[C@H](Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2ccc(CO)cc2)C1=O |
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| Structure | 
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