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Reaction Details
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TargetTrypsin-1
LigandBDBM50288406
Substrate/Competitorn/a
Meas. Tech.ChEBML_210656
Ki 0.045000±n/a nM
Citation Quan MLWityak JDominguez CDuncia JVKettner CAEllis CDLiauw AYPark JMSantella JBKnabb RMThoolen MJWeber PCWexler RR Biaryl substituted alkylboronate esters as thrombin inhibitors Bioorg Med Chem Lett 7:1595-1600 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
Trypsin-1
Name:Trypsin-1
Synonyms:Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | Trypsin | Trypsin I
Type:Enzyme
Mol. Mass.:26557.80
Organism:Homo sapiens (Human)
Description:P07477
Residue:247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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  Blast E-value cutoff:
BDBM50288406
n/a
NameBDBM50288406
Synonyms:1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid (1-dihydroxyboranyl-4-guanidino-butyl)-amide | AC-(D)PHE-PRO-BOROARG-OH | CHEMBL290376
TypeSmall organic molecule
Emp. Form.C21H33BN6O5
Mol. Mass.460.335
SMILESCC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)B(O)O
Structure
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