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Reaction Details
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TargetPeptidylprolyl isomerase
LigandBDBM50068572
Substrate/Competitorn/a
Meas. Tech.ChEBML_66431
Ki 30±n/a nM
Citation Hamilton, GSHuang, WConnolly, MARoss, DTGuo, HValentine, HLSuzdak, PDSteiner, JP FKBP12-binding domain analogues of FK506 are potent, nonimmunosuppressive neurotrophic agents in vitro and promote recovery in a mouse model of parkinson's disease Bioorg Med Chem Lett7:1785-1790 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
Peptidylprolyl isomerase
Name:Peptidylprolyl isomerase
Synonyms:FK506 binding protein 12
Type:PROTEIN
Mol. Mass.:11960.67
Organism:Gallus gallus
Description:ChEMBL_66431
Residue:108
Sequence:
MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFRFKIGRQEVIKGF
EEGVTQMSLGQRAKLTCTPEMAYGATGHPGVIPPNATLLFDVELLRLE
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  Blast E-value cutoff:
BDBM50068572
n/a
NameBDBM50068572
Synonyms:1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 4-phenyl-1-(3-phenyl-propyl)-butyl ester | CHEMBL298173
TypeSmall organic molecule
Emp. Form.C32H43NO4
Mol. Mass.505.6881
SMILESCCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCCc1ccccc1)CCCc1ccccc1
Structure
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