| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50290169 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_30920 |
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| Ki | 3.9±n/a nM |
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| Citation |  Shimada, J; Koike, N; Nonaka, H; Shiozaki, S; Yanagawa, K; Kanda, T; Kobayashi, H; Ichimura, M; Nakamura, J; Kase, H; Suzuki, F Adenosine A2A antagonists with potent anti-cataleptic activity Bioorg Med Chem Lett7:2349-2352 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 45015.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat A2A receptors expressed in CHO cells. |
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| Residue: | 410 |
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| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
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| BDBM50290169 |
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| n/a |
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| Name | BDBM50290169 |
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| Synonyms: | 8-[(E)-2-(4-Methoxy-2,3-dimethyl-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | CHEMBL78317 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H30N4O3 |
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| Mol. Mass. | 410.5093 |
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| SMILES | CCCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CCC)c1=O |
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| Structure | 
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