| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
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| Ligand | BDBM50032675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_195991 |
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| Ki | >1000±n/a nM |
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| Citation |  Farmer, LJ; Jeong, S; Kallel, EA; Koch, SS; Croston, GE; Flatten, KS; Heyman, RA; Nadzan, AM Synthesis and structure-activity relationships of potent retinoid X receptor ligands Bioorg Med Chem Lett7:2393-2398 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor gamma |
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| Name: | Retinoic acid receptor gamma |
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| Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50345.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458016 |
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| Residue: | 454 |
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| Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
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| BDBM50032675 |
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| n/a |
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| Name | BDBM50032675 |
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| Synonyms: | 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid | BEXAROTENE | CHEMBL1023 | p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28O2 |
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| Mol. Mass. | 348.4779 |
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| SMILES | Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C |
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| Structure | 
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