| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
|---|
| Ligand | BDBM50033079 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_196638 (CHEMBL800751) |
|---|
| Ki | 199±n/a nM |
|---|
| Citation |  Farmer, LJ; Zhi, L; Jeong, S; Kallel, EA; Croston, G; Flatten, KS; Heyman, RA; Nadzan, AM Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands Bioorg Med Chem Lett7:2747-2752 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor RXR-beta |
|---|
| Name: | Retinoic acid receptor RXR-beta |
|---|
| Synonyms: | NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56932.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_39045 |
|---|
| Residue: | 533 |
|---|
| Sequence: | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
|
|
|
|---|
| BDBM50033079 |
|---|
| n/a |
|---|
| Name | BDBM50033079 |
|---|
| Synonyms: | 4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid | CHEMBL96184 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26O2 |
|---|
| Mol. Mass. | 334.4513 |
|---|
| SMILES | CC1(C)CCC(C)(C)c2cc(ccc12)C(=C)c1ccc(cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
