| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 1 |
|---|
| Ligand | BDBM50290834 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_48698 |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Kubo, K; Shimizu, T; Ohyama, Si; Murooka, H; Nishitoba, T; Kato, S; Kobayashi, Y; Yagi, M; Isoe, T; Nakamura, K; Osawa, T; Izawa, T A novel series of 4-phenoxyquinolines: potent and highly selective inhibitors of PDGF receptor autophosphorylation Bioorg Med Chem Lett7:2935-2940 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 1 |
|---|
| Name: | Cyclin-dependent kinase 1 |
|---|
| Synonyms: | CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 34101.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P06493 |
|---|
| Residue: | 297 |
|---|
| Sequence: | MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
|
|
|
|---|
| BDBM50290834 |
|---|
| n/a |
|---|
| Name | BDBM50290834 |
|---|
| Synonyms: | 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline | CHEMBL327300 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H19NO5 |
|---|
| Mol. Mass. | 341.3579 |
|---|
| SMILES | COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
