| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50291054 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157558 |
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| Ki | 3±n/a nM |
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| Citation |  Schwartz, TM; Bundy, GL; Strohbach, JW; Thaisrivongs, S; Johnson, PD; Skulnick, HI; Tomich, PK; Lynn, JC; Chong, KT; Hinshaw, RR; Raub, TJ; Padbury, GE; Toth, LN Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors Bioorg Med Chem Lett7:399-402 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50291054 |
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| n/a |
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| Name | BDBM50291054 |
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| Synonyms: | 3-{Cyclopropyl-[3-(1-methyl-1H-imidazole-2-sulfonylmethyl)-phenyl]-methyl}-4-hydroxy-5,6,7,8,9,10-hexahydro-cycloocta[b]pyran-2-one | CHEMBL338756 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N2O5S |
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| Mol. Mass. | 482.592 |
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| SMILES | Cn1ccnc1S(=O)(=O)Cc1cccc(c1)C(C1CC1)c1c(O)c2CCCCCCc2oc1=O |
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| Structure | 
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