| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-8 |
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| Ligand | BDBM50291125 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_89094 |
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| Ki | 9300±n/a nM |
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| Citation |  Attwood, MR; Conway, EA; Dunsdon, RM; Greening, JR; Handa, BK; Jones, PS; Jordan, SC; Keech, E; Wilson, FX Peptide based inhibitors of interleukin-8: structural simplification and enhanced potency Bioorg Med Chem Lett7:429-432 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Interleukin-8 |
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| Name: | Interleukin-8 |
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| Synonyms: | CXCL8 | IL8 | IL8_HUMAN | MDNCF-a | interleukin 8 precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 11104.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_577736 |
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| Residue: | 99 |
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| Sequence: | MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPH
CANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
|
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|
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| BDBM50291125 |
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| n/a |
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| Name | BDBM50291125 |
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| Synonyms: | CHEMBL3856135 | CHEMBL411548 | Interleukin-8 inhibitor, 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C114H147N23O36S2 |
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| Mol. Mass. | 2479.649 |
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| SMILES | CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCCC1C(N)=O |r| |
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| Structure | 
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