| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50292430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_481041 (CHEMBL996660) |
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| IC50 | 9000±n/a nM |
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| Citation |  Mierzwa, R; King, A; Conover, MA; Tozzi, S; Puar, MS; Patel, M; Coval, SJ; Pomponi, SA Verongamine, a Novel Bromotyrosine-Derived Histamine H3-Antagonist from the Marine Sponge Verongula gigantea J Nat Prod57:175-177 (1994) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50292430 |
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| n/a |
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| Name | BDBM50292430 |
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| Synonyms: | CHEMBL479515 | aerophobin-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16Br2N4O4 |
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| Mol. Mass. | 476.12 |
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| SMILES | COC1=C(Br)C(O)C2(CC(=NO2)C(=O)NCCc2cnc[nH]2)C=C1Br |c:2,9,24| |
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| Structure | 
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