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TargetDNA polymerase beta
LigandBDBM50250356
Substrate/Competitorn/a
Meas. Tech.ChEMBL_546495
IC50 7400±n/a nM
Citation Pengsuparp TCai LConstant HFong HHLin LZKinghorn ADPezzuto JMCordell GAIngolfsdöttir KWagner HHughes SH Mechanistic Evaluation of New Plant-Derived Compounds That Inhibit HIV-1 Reverse Transcriptase J Nat Prod 58:1024-1031 (1995) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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  Blast E-value cutoff:
BDBM50250356
n/a
NameBDBM50250356
Synonyms:(+)-protolichesterinic acid | CHEMBL490329 | protolichesterinic acid
TypeSmall organic molecule
Emp. Form.C19H32O4
Mol. Mass.324.455
SMILESCCCCCCCCCCCCC[C@@H]1OC(=O)C(=C)[C@H]1C(O)=O |r|
Structure
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