| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50250356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_546495 (CHEMBL1026664) |
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| IC50 | 7400±n/a nM |
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| Citation |  Pengsuparp, T; Cai, L; Constant, H; Fong, HH; Lin, LZ; Kinghorn, AD; Pezzuto, JM; Cordell, GA; Ingolfsdöttir, K; Wagner, H; Hughes, SH Mechanistic Evaluation of New Plant-Derived Compounds That Inhibit HIV-1 Reverse Transcriptase J Nat Prod58:1024-1031 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB |
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| Type: | Protein |
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| Mol. Mass.: | 38188.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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| BDBM50250356 |
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| n/a |
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| Name | BDBM50250356 |
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| Synonyms: | (+)-protolichesterinic acid | CHEMBL490329 | protolichesterinic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C19H32O4 |
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| Mol. Mass. | 324.455 |
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| SMILES | CCCCCCCCCCCCC[C@@H]1OC(=O)C(=C)[C@H]1C(O)=O |r| |
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| Structure | 
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