Reaction Details |
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Target | Ribonuclease pancreatic |
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Ligand | BDBM50292719 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_493877 (CHEMBL944248) |
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Ki | 172000±n/a nM |
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Citation | Samanta, A; Leonidas, DD; Dasgupta, S; Pathak, T; Zographos, SE; Oikonomakos, NG Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J Med Chem52:932-42 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Ribonuclease pancreatic |
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Name: | Ribonuclease pancreatic |
Synonyms: | CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1 |
Type: | Enzyme |
Mol. Mass.: | 16468.79 |
Organism: | Bison bison (American bison) |
Description: | carboxamidomethylated RNase A |
Residue: | 150 |
Sequence: | MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRN
LTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPN
CAYKTTQANKHIIVACEGNPYVPVHFDASV
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BDBM50292719 |
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n/a |
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Name | BDBM50292719 |
Synonyms: | 5'-deoxy-5'-N-piperidinouridine | CHEMBL444258 |
Type | Small organic molecule |
Emp. Form. | C14H21N3O5 |
Mol. Mass. | 311.3336 |
SMILES | O[C@@H]1[C@@H](CN2CCCCC2)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| |
Structure |
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