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TargetVesicular acetylcholine transporter
LigandBDBM50292908
Substrate/Competitorn/a
Meas. Tech.ChEMBL_494628
Ki 0.250000±n/a nM
Citation Tu ZEfange SMXu JLi SJones LAParsons SMMach RH Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. J Med Chem 52:1358-69 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vesicular acetylcholine transporter
Name:Vesicular acetylcholine transporter
Synonyms:Solute carrier family 18 member 3 | VAChT
Type:PROTEIN
Mol. Mass.:56900.67
Organism:Homo sapiens (Human)
Description:ChEMBL_1507628
Residue:532
Sequence:
MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
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  Blast E-value cutoff:
BDBM50292908
n/a
NameBDBM50292908
Synonyms:(+/-)-trans-2-Hydroxy-3-(4-(4-bromobenzoyl)piperidino)tetralin Hydrochloride | CHEMBL473547
TypeSmall organic molecule
Emp. Form.C22H24BrNO2
Mol. Mass.414.335
SMILESO[C@@H]1Cc2ccccc2C[C@H]1N1CCC(CC1)C(=O)c1ccc(Br)cc1 |r|
Structure
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