Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGALR1
LigandBDBM50293029
Substrate/Competitorn/a
Meas. Tech.ChEMBL_518781
Ki 1.3±n/a nM
Citation Zhang LRobertson CRGreen BRPruess THWhite HSBulaj G Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues. J Med Chem 52:1310-6 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
GALR1
Name:GALR1
Synonyms:GAL1-R | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1
Type:Enzyme Catalytic Domain
Mol. Mass.:38976.60
Organism:Homo sapiens (Human)
Description:Galanin R1 GALR1 HUMAN::P47211
Residue:349
Sequence:
MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLAR
SKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSML
VSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR
ASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEA
SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNP
IIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50293029
n/a
NameBDBM50293029
Synonyms:(Sar)WTLNSAGYLLGPKK(Lys-decanoyl)K | CHEMBL460706
TypeSmall organic molecule
Emp. Form.C98H161N23O23
Mol. Mass.2029.4672
SMILESCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: