| Reaction Details |
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 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
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| Ligand | BDBM50293101 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_514917 (CHEMBL972643) |
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| IC50 | 54±n/a nM |
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| Citation |  Auld, DS; Zhang, YQ; Southall, NT; Rai, G; Landsman, M; MacLure, J; Langevin, D; Thomas, CJ; Austin, CP; Inglese, J A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem52:1450-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Luciferin 4-monooxygenase |
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| Name: | Luciferin 4-monooxygenase |
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| Synonyms: | LUCI_PHOPE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60658.88 |
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| Organism: | Photuris pennsylvanica |
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| Description: | ChEMBL_514919 |
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| Residue: | 545 |
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| Sequence: | MEDKNILYGPEPFHPLADGTAGEQMFYALSRYADISGCIALTNAHTKENVLYEEFLKLSC
RLAESFKKYGLKQNDTIAVCSENGLQFFLPLIASLYLGIIAAPVSDKYIERELIHSLGIV
KPRIIFCSKNTFQKVLNVKSKLKYVETIIILDLNEDLGGYQCLNNFISQNSDINLDVKKF
KPNSFNRDDQVALVMFSSGTTGVSKGVMLTHKNIVARFSHCKDPTFGNAINPTTAILTVI
PFHHGFGMTTTLGYFTCGFRVALMHTFEEKLFLQSLQDYKVESTLLVPTLMAFFPKSALV
EKYDLSHLKEIASGGAPLSKEIGEMVKKRFKLNFVRQGYGLTETTSAVLITPDTDVRPGS
TGKIVPFHAVKVVDPTTGKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKDGWLRSG
DIAYYDNDGHFYIVDRLKSLIKYKGYQVAPAEIEGILLQHPYIVDAGVTGIPDEAAGELP
AAGVVVQTGKYLNEQIVQNFVSSQVSTAKWLRGGVKFLDEIPKGSTGKIDRKVLRQMFEK
HKSKL
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| BDBM50293101 |
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| n/a |
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| Name | BDBM50293101 |
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| Synonyms: | 5-(2,4-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole | CHEMBL473735 | cid_893238 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2O3 |
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| Mol. Mass. | 282.294 |
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| SMILES | COc1ccc(-c2nc(no2)-c2ccccc2)c(OC)c1 |
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| Structure | 
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