| Reaction Details |
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 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
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| Ligand | BDBM50129784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_514920 (CHEMBL972646) |
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| IC50 | 700±n/a nM |
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| Citation |  Auld, DS; Zhang, YQ; Southall, NT; Rai, G; Landsman, M; MacLure, J; Langevin, D; Thomas, CJ; Austin, CP; Inglese, J A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem52:1450-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Luciferin 4-monooxygenase |
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| Name: | Luciferin 4-monooxygenase |
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| Synonyms: | LUCI_PHOPY | Luciferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60747.46 |
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| Organism: | Photinus pyralis |
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| Description: | ChEMBL_938513 |
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| Residue: | 550 |
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| Sequence: | MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMS
VRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNI
SQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYD
FVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSV
VPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTL
IDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPG
AVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHS
GDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGEL
PAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILI
KAKKGGKSKL
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| BDBM50129784 |
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| n/a |
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| Name | BDBM50129784 |
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| Synonyms: | 4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylaniline | CHEMBL328430 | [4-(6-Methoxy-benzothiazol-2-yl)-phenyl]-dimethyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2OS |
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| Mol. Mass. | 284.376 |
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| SMILES | COc1ccc2nc(sc2c1)-c1ccc(cc1)N(C)C |
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| Structure | 
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