| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
|---|
| Ligand | BDBM50293100 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_514916 (CHEMBL972642) |
|---|
| IC50 | 1400±n/a nM |
|---|
| Citation |  Auld, DS; Zhang, YQ; Southall, NT; Rai, G; Landsman, M; MacLure, J; Langevin, D; Thomas, CJ; Austin, CP; Inglese, J A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem52:1450-8 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Luciferin 4-monooxygenase |
|---|
| Name: | Luciferin 4-monooxygenase |
|---|
| Synonyms: | LUCI_PHOPY | Luciferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60747.46 |
|---|
| Organism: | Photinus pyralis |
|---|
| Description: | ChEMBL_938513 |
|---|
| Residue: | 550 |
|---|
| Sequence: | MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMS
VRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNI
SQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYD
FVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSV
VPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTL
IDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPG
AVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHS
GDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGEL
PAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILI
KAKKGGKSKL
|
|
|
|---|
| BDBM50293100 |
|---|
| n/a |
|---|
| Name | BDBM50293100 |
|---|
| Synonyms: | 3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl biphenyl-4-carboxylate | CHEMBL460694 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H13N3O3 |
|---|
| Mol. Mass. | 343.3355 |
|---|
| SMILES | O=C(Oc1nc(no1)-c1ccccn1)c1ccc(cc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
