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TargetLuciferin 4-monooxygenase
LigandBDBM50129784
Substrate/Competitorn/a
Meas. Tech.ChEMBL_514921
IC50>50000±n/a nM
Citation Auld DSZhang YQSouthall NTRai GLandsman MMacLure JLangevin DThomas CJAustin CPInglese J A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem 52:1450-8 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Luciferin 4-monooxygenase
Name:Luciferin 4-monooxygenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:60658.88
Organism:Photuris pennsylvanica
Description:ChEMBL_514919
Residue:545
Sequence:
MEDKNILYGPEPFHPLADGTAGEQMFYALSRYADISGCIALTNAHTKENVLYEEFLKLSC
RLAESFKKYGLKQNDTIAVCSENGLQFFLPLIASLYLGIIAAPVSDKYIERELIHSLGIV
KPRIIFCSKNTFQKVLNVKSKLKYVETIIILDLNEDLGGYQCLNNFISQNSDINLDVKKF
KPNSFNRDDQVALVMFSSGTTGVSKGVMLTHKNIVARFSHCKDPTFGNAINPTTAILTVI
PFHHGFGMTTTLGYFTCGFRVALMHTFEEKLFLQSLQDYKVESTLLVPTLMAFFPKSALV
EKYDLSHLKEIASGGAPLSKEIGEMVKKRFKLNFVRQGYGLTETTSAVLITPDTDVRPGS
TGKIVPFHAVKVVDPTTGKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKDGWLRSG
DIAYYDNDGHFYIVDRLKSLIKYKGYQVAPAEIEGILLQHPYIVDAGVTGIPDEAAGELP
AAGVVVQTGKYLNEQIVQNFVSSQVSTAKWLRGGVKFLDEIPKGSTGKIDRKVLRQMFEK
HKSKL
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  Blast E-value cutoff:
BDBM50129784
n/a
NameBDBM50129784
Synonyms:4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylaniline | CHEMBL328430 | [4-(6-Methoxy-benzothiazol-2-yl)-phenyl]-dimethyl-amine
TypeSmall organic molecule
Emp. Form.C16H16N2OS
Mol. Mass.284.376
SMILESCOc1ccc2nc(sc2c1)-c1ccc(cc1)N(C)C
Structure
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