| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Ligand | BDBM50293264 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_492500 (CHEMBL950413) |
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| Ki | 99±n/a nM |
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| Citation |  Nilsson, J; Nielsen, EŘ; Liljefors, T; Nielsen, M; Sterner, O Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors. Bioorg Med Chem Lett18:5713-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Synonyms: | GABA A anti-Alpha3 | GABA A receptor alpha-3/beta-2/gamma-2 | GABA receptor alpha-3 subunit | GBRA3_RAT | Gabra-3 | Gabra3 | Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55444.88 |
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| Organism: | RAT |
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| Description: | GABA A Alpha3Beta2Gamma2 0 RAT::P20236 |
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| Residue: | 493 |
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| Sequence: | MITTQMWHFYVTRVGLLLLISILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKAEVIYSWTLGKNKSVEVAQDGSRL
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVN
YFTKRSWAWEGKKVPEALEMKKKTPAAPTKKTSTTFNIVGTTYPINLALDTEFSTISKAA
AAPSASSTPTVIASPKTTYVQDSPAETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV
NRESAIKGMIRKQ
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| BDBM50293264 |
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| n/a |
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| Name | BDBM50293264 |
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| Synonyms: | 2-(5-bromo-2-hydroxyphenyl)-6-methylquinolin-4(1H)-one | CHEMBL452728 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12BrNO2 |
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| Mol. Mass. | 330.176 |
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| SMILES | Cc1ccc2nc(cc(O)c2c1)-c1cc(Br)ccc1O |
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| Structure | 
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