| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase-like amidohydrolase |
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| Ligand | BDBM19149 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571661 (CHEMBL1031316) |
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| Ki | 1300±n/a nM |
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| Citation |  Riester, D; Hildmann, C; Haus, P; Galetovic, A; Schober, A; Schwienhorst, A; Meyer-Almes, FJ Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. Bioorg Med Chem Lett19:3651-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase-like amidohydrolase |
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| Name: | Histone deacetylase-like amidohydrolase |
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| Synonyms: | HDAH_ALCSD | hdaH | hdaH1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39419.78 |
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| Organism: | Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188)) |
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| Description: | ChEMBL_827139 |
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| Residue: | 369 |
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| Sequence: | MAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLT
PIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVE
LTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWD
VHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAA
YLHAMDQVVLHALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADIC
DGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEE
IVPLLADIR
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| BDBM19149 |
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| n/a |
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| Name | BDBM19149 |
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| Synonyms: | CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA | US10011611, SAHA | US10188756, Compound SAHA | US11207431, SAHA | US11505523, Compound SAHA | US9115116, SAHA | US9353061, SAHA | US9428447, SAHA | US9695181, Vorinostat | Vorinostat | Zolinza | cid_5311 | suberoylanilide hydroxamic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N2O3 |
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| Mol. Mass. | 264.3202 |
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| SMILES | ONC(=O)CCCCCCC(=O)Nc1ccccc1 |
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| Structure | 
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