| Reaction Details |
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 | Report a problem with these data |
| Target | Kinesin-like protein KIF3B |
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| Ligand | BDBM50293773 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571922 (CHEMBL1035571) |
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| IC50 | >50000±n/a nM |
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| Citation |  Lahue, BR; Ma, Y; Shipps, GW; Seghezzi, W; Herbst, R Substituted benzimidazoles: A novel chemotype for small molecule hKSP inhibitors. Bioorg Med Chem Lett19:3405-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kinesin-like protein KIF3B |
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| Name: | Kinesin-like protein KIF3B |
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| Synonyms: | KIAA0359 | KIF3B | KIF3B_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 85132.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_571922 |
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| Residue: | 747 |
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| Sequence: | MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD
AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP
NSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLS
SFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGK
LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRL
LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQE
EIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEK
LEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKN
IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK
LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIM
NRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENI
VLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSG
RKSGSSSSSSGTPASQLYPQSRGLVPK
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| BDBM50293773 |
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| n/a |
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| Name | BDBM50293773 |
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| Synonyms: | 2-(4-methoxybenzylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid | CHEMBL559958 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20F3N3O3 |
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| Mol. Mass. | 455.4291 |
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| SMILES | COc1ccc(CNc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1 |
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| Structure | 
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