| Reaction Details |
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 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
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| Ligand | BDBM50293860 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_572601 (CHEMBL1026025) |
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| IC50 | 11400±n/a nM |
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| Citation |  Mahindroo, N; Connelly, MC; Punchihewa, C; Kimura, H; Smeltzer, MP; Wu, S; Fujii, N Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription. J Med Chem52:4277-87 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Zinc finger protein GLI1 |
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| Name: | Zinc finger protein GLI1 |
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| Synonyms: | GLI | GLI1 | GLI1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 117920.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_537531 |
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| Residue: | 1106 |
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| Sequence: | MFNSMTPPPISSYGEPCCLRPLPSQGAPSVGTEGLSGPPFCHQANLMSGPHSYGPARETN
SCTEGPLFSSPRSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSPGGS
YGHLSIGTMSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLK
SELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWD
GCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKP
HKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEK
PYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREG
GPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSS
LDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLE
RRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGG
TSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSL
GCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNP
YMDFPPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETW
GEFPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEG
PPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCN
YVQSQQELLWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHK
SGSYPTPSPCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLG
GGPALYPPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGP
PNMAVGNMSVLLRSLPGETEFLNSSA
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| BDBM50293860 |
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| n/a |
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| Name | BDBM50293860 |
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| Synonyms: | (S)-2-(3-Benzoylphenyl)-N-(3,4-dihydroxyphenethyl)propanamide | CHEMBL560356 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23NO4 |
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| Mol. Mass. | 377.433 |
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| SMILES | C[C@H](C(=O)NCCc1ccc(O)c(O)c1)c1cccc(Oc2ccccc2)c1 |r| |
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| Structure | 
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