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TargetPolyamine oxidase
LigandBDBM50294106
Substrate/Competitorn/a
Meas. Tech.ChEMBL_570655
pH6.5±n/a
Ki 1.1±n/a nM
Commentsextracted
Citation Manetti FCona AAngeli LMugnaini CRaffi FCapone CDreassi EZizzari ATTisi AFederico RBotta M Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase. J Med Chem 52:4774-85 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Polyamine oxidase
Name:Polyamine oxidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:56339.65
Organism:Zea mays
Description:ChEMBL_570655
Residue:500
Sequence:
MSSSPSFGLLAVAALLLALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLL
ILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYL
AQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPN
GPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYL
AGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQ
SDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVW
QEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPR
WWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAE
ILINCAQKKMCKYHVQGKYD
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  Blast E-value cutoff:
BDBM50294106
n/a
NameBDBM50294106
Synonyms:1-(Guanidino)-17-(N1-(gamma-methylallyl)guanidino)-9-azaheptadecane tris(trifluoroacetate) | CHEMBL550690
TypeSmall organic molecule
Emp. Form.C22H47N7
Mol. Mass.409.6555
SMILES[#6]\[#6]=[#6]\[#6]-[#7]-[#6](-[#7])=[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7] |w:7.7|
Structure
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