| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50294115 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_571059 (CHEMBL1027776) |
|---|
| Ki | 0.63±n/a nM |
|---|
| Citation |  Ehrlich, K; Götz, A; Bollinger, S; Tschammer, N; Bettinetti, L; Härterich, S; Hübner, H; Lanig, H; Gmeiner, P Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding. J Med Chem52:4923-35 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50294115 |
|---|
| n/a |
|---|
| Name | BDBM50294115 |
|---|
| Synonyms: | CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piperazin-1-yl)butyl)H-pyrazolo[1,5-a]pyridine-2-carboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H29N5OS |
|---|
| Mol. Mass. | 423.574 |
|---|
| SMILES | CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
