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TargetD(2) dopamine receptor
LigandBDBM50294118
Substrate/Competitorn/a
Meas. Tech.ChEMBL_570891
Ki 220±n/a nM
Citation Ehrlich KGötz ABollinger STschammer NBettinetti LHärterich SHübner HLanig HGmeiner P Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding. J Med Chem 52:4923-35 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM50294118
n/a
NameBDBM50294118
Synonyms:2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]-pyridine | CHEMBL561622
TypeSmall organic molecule
Emp. Form.C22H27ClN4
Mol. Mass.382.93
SMILESClc1ccc(cc1)N1CCN(CCCCCc2cc3ccccn3n2)CC1
Structure
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