| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM22914 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_577510 (CHEMBL1057862) |
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| Ki | 4.8±n/a nM |
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| Citation |  Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies. Bioorg Med Chem Lett19:4075-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_MOUSE | Hrh3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48560.37 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_988451 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM22914 |
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| n/a |
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| Name | BDBM22914 |
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| Synonyms: | CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide | Thioperamide | US11622967, Compound Thioperamide |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N4S |
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| Mol. Mass. | 292.443 |
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| SMILES | S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 |
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| Structure | 
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