Reaction Details |
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Target | Cyclin-dependent kinase 1 |
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Ligand | BDBM50295351 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_578404 (CHEMBL1058744) |
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IC50 | >33000±n/a nM |
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Citation | Corbel, C; Haddoub, R; Guiffant, D; Lozach, O; Gueyrard, D; Lemoine, J; Ratin, M; Meijer, L; Bach, S; Goekjian, P Identification of potential cellular targets of aloisine A by affinity chromatography. Bioorg Med Chem17:5572-82 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Cyclin-dependent kinase 1 |
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Name: | Cyclin-dependent kinase 1 |
Synonyms: | CDC28 | CDK1 | CDK1_YEAST | Cell division control protein 28 | HSL5 | SRM5 |
Type: | PROTEIN |
Mol. Mass.: | 34067.63 |
Organism: | Saccharomyces cerevisiae |
Description: | ChEMBL_563811 |
Residue: | 298 |
Sequence: | MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREIS
LLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQL
CKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP
EVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIV
YLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES
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BDBM50295351 |
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n/a |
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Name | BDBM50295351 |
Synonyms: | CHEMBL560452 | N-methyl-aloisine A |
Type | Small organic molecule |
Emp. Form. | C17H19N3O |
Mol. Mass. | 281.3523 |
SMILES | CCCCc1c(-c2ccc(O)cc2)n(C)c2nccnc12 |
Structure |
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