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TargetCyclin-dependent kinase 1
LigandBDBM50295351
Substrate/Competitorn/a
Meas. Tech.ChEMBL_578404 (CHEMBL1058744)
IC50>33000±n/a nM
Citation Corbel, CHaddoub, RGuiffant, DLozach, OGueyrard, DLemoine, JRatin, MMeijer, LBach, SGoekjian, P Identification of potential cellular targets of aloisine A by affinity chromatography. Bioorg Med Chem17:5572-82 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cyclin-dependent kinase 1
Name:Cyclin-dependent kinase 1
Synonyms:CDC28 | CDK1 | CDK1_YEAST | Cell division control protein 28 | HSL5 | SRM5
Type:PROTEIN
Mol. Mass.:34067.63
Organism:Saccharomyces cerevisiae
Description:ChEMBL_563811
Residue:298
Sequence:
MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREIS
LLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQL
CKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP
EVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIV
YLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50295351
n/a
NameBDBM50295351
Synonyms:CHEMBL560452 | N-methyl-aloisine A
TypeSmall organic molecule
Emp. Form.C17H19N3O
Mol. Mass.281.3523
SMILESCCCCc1c(-c2ccc(O)cc2)n(C)c2nccnc12
Structure
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