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Target5-hydroxytryptamine receptor 2A
LigandBDBM50297304
Substrate/Competitorn/a
Meas. Tech.ChEMBL_582984
Ki 0.14±n/a nM
Citation Moree WJLi BFJovic FCoon TYu JGross RSTucci FMarinkovic DZamani-Kord SMalany SBradbury MJHernandez LMO'Brien ZWen JWang HHoare SRPetroski RESacaan AMadan ACrowe PDBeaton G Characterization of novel selective H1-antihistamines for clinical evaluation in the treatment of insomnia. J Med Chem 52:5307-10 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:Dopamine D2 receptor and serotonin 2a receptor
Synonyms:5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | HTR2 | HTR2A | Serotonin receptor 2A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52607.65
Organism:Homo sapiens (Human)
Description:n/a
Residue:471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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  Blast E-value cutoff:
BDBM50297304
n/a
NameBDBM50297304
Synonyms:CHEMBL560741 | {2-[3-(4-Fluoro-benzyl)-1H-inden-2-yl]-ethyl}-dimethyl-amine
TypeSmall organic molecule
Emp. Form.C20H22FN
Mol. Mass.295.3938
SMILESCN(C)CCC1=C(Cc2ccc(F)cc2)c2ccccc2C1 |c:5|
Structure
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