| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50297606 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_583691 (CHEMBL1061737) |
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| EC50 | 7.9±n/a nM |
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| Citation |  Ryckmans, T; Edwards, MP; Horne, VA; Correia, AM; Owen, DR; Thompson, LR; Tran, I; Tutt, MF; Young, T Rapid assessment of a novel series of selective CB(2) agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis. Bioorg Med Chem Lett19:4406-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50297606 |
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| n/a |
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| Name | BDBM50297606 |
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| Synonyms: | 2-tert-butyl-1-(cyclopropylmethyl)-5-(phenylsulfonyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine | CHEMBL564244 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27N3O2S |
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| Mol. Mass. | 373.512 |
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| SMILES | CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1ccccc1 |
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| Structure | 
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