| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50297597 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_583693 (CHEMBL1061739) |
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| EC50 | 7500±n/a nM |
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| Citation |  Ryckmans, T; Edwards, MP; Horne, VA; Correia, AM; Owen, DR; Thompson, LR; Tran, I; Tutt, MF; Young, T Rapid assessment of a novel series of selective CB(2) agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis. Bioorg Med Chem Lett19:4406-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50297597 |
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| n/a |
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| Name | BDBM50297597 |
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| Synonyms: | 4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-ylsulfonyl)-3,5-dimethylisoxazole | CHEMBL562150 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28N4O3S |
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| Mol. Mass. | 392.516 |
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| SMILES | Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C |
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| Structure | 
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