Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetProstate-specific antigen
LigandBDBM50298754
Substrate/Competitorn/a
Meas. Tech.ChEMBL_588029 (CHEMBL1048364)
Ki 2.5±n/a nM
Citation LeBeau, AMBanerjee, SRPomper, MGMease, RCDenmeade, SR Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer. Bioorg Med Chem17:4888-93 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostate-specific antigen
Name:Prostate-specific antigen
Synonyms:APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin
Type:PROTEIN
Mol. Mass.:28747.53
Organism:Homo sapiens (Human)
Description:ChEMBL_959198
Residue:261
Sequence:
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
SLYTKVVHYRKWIKDTIVANP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50298754
n/a
NameBDBM50298754
Synonyms:(5S,8S,11S,14S,17R)-11-(4-aminobutyl)-5,8-bis(hydroxymethyl)-14-isobutyl-10,19-dimethyl-3,6,9,12,15-pentaoxo-1-phenyl-2-oxa-4,7,10,13,16-pentaazaicosan-17-ylboronic acid | CHEMBL574538
TypeSmall organic molecule
Emp. Form.C32H55BN6O10
Mol. Mass.694.624
SMILESCC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)N(C)C(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1)B(O)O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: