| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Receptor-type tyrosine-protein phosphatase alpha |
|---|
| Ligand | BDBM50118796 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_590760 (CHEMBL1037598) |
|---|
| Ki | 800000±n/a nM |
|---|
| Citation |  Vidovic, D; Schürer, SC Knowledge-based characterization of similarity relationships in the human protein-tyrosine phosphatase family for rational inhibitor design. J Med Chem52:6649-59 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Receptor-type tyrosine-protein phosphatase alpha |
|---|
| Name: | Receptor-type tyrosine-protein phosphatase alpha |
|---|
| Synonyms: | PTPA | PTPRA | PTPRA_HUMAN | PTPRL2 | Protein-tyrosine phosphatase alpha |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 90719.02 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P18433 |
|---|
| Residue: | 802 |
|---|
| Sequence: | MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY
KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL
FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW
TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ
RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL
TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV
ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ
QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ
YEFCYKVVQEYIDAFSDYANFK
|
|
|
|---|
| BDBM50118796 |
|---|
| n/a |
|---|
| Name | BDBM50118796 |
|---|
| Synonyms: | 6-(OXALYL-AMINO)-1H-INDOLE-5-CARBOXYLIC ACID | 6-(carboxyformamido)-1H-indole-5-carboxylic acid | CHEMBL342478 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H8N2O5 |
|---|
| Mol. Mass. | 248.1916 |
|---|
| SMILES | OC(=O)C(=O)Nc1cc2[nH]ccc2cc1C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
