| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 1 |
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| Ligand | BDBM50299910 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_594452 (CHEMBL1041501) |
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| IC50 | >1E4±n/a nM |
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| Citation |  Okamoto, M; Takayama, K; Shimizu, T; Ishida, K; Takahashi, O; Furuya, T Identification of death-associated protein kinases inhibitors using structure-based virtual screening. J Med Chem52:7323-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 1 |
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| Name: | Mitogen-activated protein kinase 1 |
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| Synonyms: | ERK2 | ERT1 | Extracellular signal-regulated kinase 2 | Extracellular signal-regulated kinase 2 (ERK-2) | Extracellular signal-regulated kinase 2 (ERK2) | MAP Kinase 2/ERK2 | MAPK 2 | MAPK1 | MK01_HUMAN | Mitogen activated kinase 1 (ERK-2) | Mitogen-activated protein kinase 1 (ERK-2) | Mitogen-activated protein kinase 1 (ERK2) | Mitogen-activated protein kinase 2 | PRKM1 | PRKM2 | p42-MAPK |
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| Type: | Ser/Thr Protein Kinase |
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| Mol. Mass.: | 41392.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28482 |
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| Residue: | 360 |
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| Sequence: | MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
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| BDBM50299910 |
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| n/a |
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| Name | BDBM50299910 |
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| Synonyms: | 4-(pyridin-3-ylmethylene)-2-styryloxazol-5(4H)-one | CHEMBL565286 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12N2O2 |
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| Mol. Mass. | 276.2894 |
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| SMILES | O=C1OC(\C=C\c2ccccc2)=N/C/1=C\c1cccnc1 |c:12| |
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| Structure | 
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