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TargetDNA polymerase beta
LigandBDBM50300194
Substrate/Competitorn/a
Meas. Tech.ChEMBL_592718
IC50>2E4±n/a nM
Citation Yin ZChen YLKondreddi RRChan WLWang GNg RHLim JYLee WYJeyaraj DANiyomrattanakit PWen DChao AGlickman JFVoshol HMueller DSpanka CDressler SNilar SVasudevan SGShi PYKeller TH N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase. J Med Chem 52:7934-7 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50300194
n/a
NameBDBM50300194
Synonyms:2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylamino]-4-fluoro-benzoic acid | CHEMBL584918
TypeSmall organic molecule
Emp. Form.C23H18FN3O4S
Mol. Mass.451.47
SMILESOC(=O)c1ccc(F)cc1NS(=O)(=O)c1cccc(c1)-c1cnn(Cc2ccccc2)c1
Structure
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