Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50300442 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_591964 (CHEMBL1047527) | ||
Ki | 0.180000±n/a nM | ||
Citation | Marton, J; Schoultz, BW; Hjørnevik, T; Drzezga, A; Yousefi, BH; Wester, HJ; Willoch, F; Henriksen, G Synthesis and evaluation of a full-agonist orvinol for PET-imaging of opioid receptors: [11C]PEO. J Med Chem52:5586-9 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
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BDBM50300442 | |||
n/a | |||
Name | BDBM50300442 | ||
Synonyms: | (20R)-4,5-alpha-Epoxy-17-methyl-3-hydroxy-6-methoxy-alpha-17-dimethyl-alpha-(2-phenylethyl)-6,14-ethenomorphinan-7-methanol | CHEMBL578629 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H35NO4 | ||
Mol. Mass. | 473.6032 | ||
SMILES | CO[C@]12C=C[C@@]3(C[C@@H]1[C@@](C)(O)CCc1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1C)c45 |r,wU:19.36,8.10,wD:5.4,7.8,8.11,2.1,28.29,29.38,c:3,(.49,-5.98,;1.05,-4.54,;.09,-3.34,;-.99,-2.33,;-.42,-1.28,;-1.5,-.69,;.04,-.66,;.84,-1.99,;2.38,-1.96,;1.59,-.62,;3.17,-3.28,;3.12,-.61,;4.66,-.59,;5.41,.76,;6.94,.78,;7.69,2.12,;6.9,3.44,;5.35,3.41,;4.61,2.07,;-2.31,.63,;-3.86,.59,;-4.59,-.77,;-6.12,-.8,;-6.86,-2.16,;-6.06,-3.47,;-6.8,-4.82,;-4.52,-3.44,;-2.66,-4.42,;-1.46,-3.37,;-2.25,-2.05,;-3.44,-.93,;-3.43,1.87,;-2.03,1.87,;-.83,2.83,;-3.78,-2.08,)| | ||
Structure |