| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear factor NF-kappa-B p105 subunit |
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| Ligand | BDBM50300850 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_598993 (CHEMBL1041917) |
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| IC50 | 110000±n/a nM |
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| Citation |  Kobayashi, T; Yoshimori, A; Kino, K; Komori, R; Miyazawa, H; Tanuma, SI A new small molecule that directly inhibits the DNA binding of NF-kappaB. Bioorg Med Chem17:5293-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear factor NF-kappa-B p105 subunit |
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| Name: | Nuclear factor NF-kappa-B p105 subunit |
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| Synonyms: | NFKB1 | NFKB1_HUMAN | Nuclear factor NF-kappa-B (NF-kB) | Nuclear factor NF-kappa-B complex | Nuclear factor NF-kappa-B p105 subunit |
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| Type: | Protein |
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| Mol. Mass.: | 105329.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P19838 |
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| Residue: | 968 |
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| Sequence: | MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED
GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQA
EGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF
SPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ
RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFH
PGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGE
VTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQD
ENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVED
LLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMM
SNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGT
TPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAT
SWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLG
LGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQ
AHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQ
EGPLEGKI
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| BDBM50300850 |
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| n/a |
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| Name | BDBM50300850 |
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| Synonyms: | 4,6-dichloro-N-(4-chlorophenyl)-1,3,5-triazin-2-amine | CHEMBL577302 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H5Cl3N4 |
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| Mol. Mass. | 275.522 |
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| SMILES | Clc1ccc(Nc2nc(Cl)nc(Cl)n2)cc1 |
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| Structure | 
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