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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2A | ||
| Ligand | BDBM50301505 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_600346 (CHEMBL1041064) | ||
| Ki | 1.9±n/a nM | ||
| Citation |  Dosa, PI; Strah-Pleynet, S; Jayakumar, H; Casper, M; Decaire, M; Xiong, Y; Lehmann, J; Choi, K; Elwell, K; Wong, A; Webb, RR; Adams, JW; Ramirez, J; Richman, JG; Thomsen, W; Semple, G; Teegarden, BR Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents. Bioorg Med Chem Lett19:5486-9 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 2A | |||
| Name: | 5-hydroxytryptamine receptor 2A | ||
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
| Type: | undefined | ||
| Mol. Mass.: | 52607.65 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28223 | ||
| Residue: | 471 | ||
| Sequence: |
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| BDBM50301505 | |||
| n/a | |||
| Name | BDBM50301505 | ||
| Synonyms: | 1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-hydroxyphenyl)urea | CHEMBL568109 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26BrN5O3 | ||
| Mol. Mass. | 500.388 | ||
| SMILES | Cn1ncc(Br)c1-c1cc(NC(=O)Nc2ccc(O)cc2)ccc1OCCN1CCCC1 |(4.26,-34.54,;4.23,-36.08,;5.46,-37.01,;4.95,-38.46,;3.41,-38.43,;2.47,-39.65,;2.97,-36.95,;1.52,-36.43,;.19,-37.2,;-1.15,-36.43,;-2.48,-37.21,;-3.81,-36.44,;-3.81,-34.9,;-5.14,-37.21,;-6.48,-36.44,;-7.82,-37.21,;-9.15,-36.44,;-9.15,-34.9,;-10.48,-34.13,;-7.82,-34.13,;-6.49,-34.89,;-1.15,-34.9,;.17,-34.12,;1.52,-34.89,;2.85,-34.12,;2.84,-32.58,;4.18,-31.8,;5.51,-32.57,;5.68,-34.09,;7.19,-34.41,;7.96,-33.07,;6.92,-31.93,)| | ||
| Structure | 
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