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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2C | ||
| Ligand | BDBM50301512 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_600347 (CHEMBL1041065) | ||
| Ki | 21.4±n/a nM | ||
| Citation |  Dosa, PI; Strah-Pleynet, S; Jayakumar, H; Casper, M; Decaire, M; Xiong, Y; Lehmann, J; Choi, K; Elwell, K; Wong, A; Webb, RR; Adams, JW; Ramirez, J; Richman, JG; Thomsen, W; Semple, G; Teegarden, BR Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents. Bioorg Med Chem Lett19:5486-9 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 2C | |||
| Name: | 5-hydroxytryptamine receptor 2C | ||
| Synonyms: | 5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 51836.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28335 | ||
| Residue: | 458 | ||
| Sequence: |
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| BDBM50301512 | |||
| n/a | |||
| Name | BDBM50301512 | ||
| Synonyms: | 1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(4-chlorophenyl)urea | CHEMBL567877 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H27BrClN5O2 | ||
| Mol. Mass. | 532.86 | ||
| SMILES | Cn1ncc(Br)c1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCCCC1 |(28.26,-6.71,;28.23,-8.25,;29.46,-9.19,;28.95,-10.64,;27.41,-10.6,;26.47,-11.83,;26.97,-9.13,;25.52,-8.61,;24.19,-9.38,;22.86,-8.61,;21.52,-9.38,;20.19,-8.62,;20.19,-7.08,;18.86,-9.39,;17.52,-8.62,;16.18,-9.39,;14.85,-8.62,;14.85,-7.08,;13.52,-6.31,;16.18,-6.31,;17.52,-7.07,;22.85,-7.08,;24.17,-6.3,;25.52,-7.07,;26.85,-6.3,;26.84,-4.76,;28.18,-3.98,;29.51,-4.75,;29.51,-6.29,;30.84,-7.05,;32.17,-6.28,;32.17,-4.74,;30.83,-3.97,)| | ||
| Structure | 
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