| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM21311 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_596087 (CHEMBL1040875) |
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| Ki | 4.6±n/a nM |
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| Citation |  Frost, JM; Dart, MJ; Tietje, KR; Garrison, TR; Grayson, GK; Daza, AV; El-Kouhen, OF; Yao, BB; Hsieh, GC; Pai, M; Zhu, CZ; Chandran, P; Meyer, MD Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity. J Med Chem53:295-315 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM21311 |
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| n/a |
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| Name | BDBM21311 |
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| Synonyms: | 4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indol-1-yl}ethyl)morpholine | CHEMBL262865 | Morpholino-ethyl analogue, 32 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H30N2O2 |
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| Mol. Mass. | 354.4858 |
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| SMILES | CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C |
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| Structure | 
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